IBD

I didn’t expect AI to change the way I code this much. This year alone, two models — Grok Code Fast 1 and GPT-5-Codex — have transformed how I work. Grok handles the small stuff, like fixing my poorly named variables. GPT-5-Codex, on the other hand, can build entire features on its own — for example, adding speech input with the Web Speech API. These tools show what’s now possible with “agentic AI” — models that can think and act for themselves. What once took weeks now takes hours, freeing up time to write posts like this (a rarity lately!). It’s hard to describe how revolutionary this feels. After years of managing several software projects, I finally have real help. ...

Over the last few years, one of the key challenges we have faced in our multi-omic translational studies is the orchestration of multi-omic datasets. In this blog post, I summarise some of the strategies we have employed to manage this complexity, after dedicating significant time to considering this problem. Industry Data Warehousing I recommend the Kimball book on data warehousing (The Data Warehouse Toolkit: The Definitive Guide to Dimensional Modelling) as a starting guide to see what other people have done in tackling ‘big data’. ...